SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer

Acquired and intrinsic radioresistance remains a major challenge during the treatment of patients with colorectal cancer (CRC). Aberrant cholesterol metabolism precipitates the development of multiple cancers. Here, we report that exogenous or endogenous cholesterol enhances the radioresistance of C...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Jin, Yuxiao, Chen, Zhiyuan, Dong, Jiali, Wang, Bin, Fan, Saijun, Yang, Xiaodong, Cui, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091817/
https://ncbi.nlm.nih.gov/pubmed/33665967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13137
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