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Non-canonical transnitrosylation network contributes to synapse loss in Alzheimer’s disease
We describe mechanistically-distinct enzymes, i.e., a kinase, a guanosine triphosphatase and a ubiquitin protein hydrolase, which function in disparate biochemical pathways, that can also act in concert to mediate a series of redox reactions. Each enzyme manifests a second, noncanonical function—tra...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091809/ https://ncbi.nlm.nih.gov/pubmed/33273062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw0843 |
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