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Exosomal HMGB1 derived from hypoxia‐conditioned bone marrow mesenchymal stem cells increases angiogenesis via the JNK/HIF‐1α pathway

Mesenchymal stem cells (MSCs) have been described to induce angiogenesis in various tissues and have been used for the development of novel cell‐based therapies. Increasing evidence suggests that MSCs execute their paracrine function via the secretion of exosomes, especially under hypoxic conditions...

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Dettagli Bibliografici
Pubblicato in:FEBS Open Bio
Autori principali: Gao, Wenling, He, Ronghan, Ren, Jianhua, Zhang, Wenhui, Wang, Kun, Zhu, Lei, Liang, Tangzhao
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091582/
https://ncbi.nlm.nih.gov/pubmed/33711197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13142
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