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Exosomal HMGB1 derived from hypoxia‐conditioned bone marrow mesenchymal stem cells increases angiogenesis via the JNK/HIF‐1α pathway

Mesenchymal stem cells (MSCs) have been described to induce angiogenesis in various tissues and have been used for the development of novel cell‐based therapies. Increasing evidence suggests that MSCs execute their paracrine function via the secretion of exosomes, especially under hypoxic conditions...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Gao, Wenling, He, Ronghan, Ren, Jianhua, Zhang, Wenhui, Wang, Kun, Zhu, Lei, Liang, Tangzhao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091582/
https://ncbi.nlm.nih.gov/pubmed/33711197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13142
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