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Azelnidipine Attenuates the Oxidative and NFκB Pathways in Amyloid-β-Stimulated Cerebral Endothelial Cells

Cerebral amyloid angiopathy (CAA), a condition depicting cerebrovascular accumulation of amyloid β-peptide (Aβ), is a common pathological manifestation in Alzheimer’s disease (AD). In this study, we investigated the effects of Azelnidipine (ALP), a dihydropyridine calcium channel blocker known for i...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Teng, Tao, Ridgley, Devin M., Tsoy, Andrey, Sun, Grace Y., Askarova, Sholpan, Lee, James C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091167/
https://ncbi.nlm.nih.gov/pubmed/30399318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00368
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