Loss of Interleukin-10 (IL-10) Signaling Promotes IL-22-Dependent Host Defenses against Acute Clostridioides difficile Infection

Infection with the bacterial pathogen Clostridioides difficile causes severe damage to the intestinal epithelium that elicits a robust inflammatory response. Markers of intestinal inflammation accurately predict clinical disease, however, the extent to which host-derived proinflammatory mediators dr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: Cribas, Emily S., Denny, Joshua E., Maslanka, Jeffrey R., Abt, Michael C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2021
Pynciau:
Host Response and Inflammation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091099/
https://ncbi.nlm.nih.gov/pubmed/33649048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00730-20
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