Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway

Tanshinone IIA, a fat-soluble diterpenoid isolated from Salvia miltiorrhiza Bunge, has been shown to attenuate the cerebral ischemic injury. The aim of this study was to examine the effects on neuroprotection and microglia activation of Tanshinone IIA. Male Sprague-Dawley rats were subjected to midd...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Song, Zhibing, Feng, Jingjing, Zhang, Qian, Deng, Shanshan, Yu, Dahai, Zhang, Yuefan, Li, Tiejun
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090935/
https://ncbi.nlm.nih.gov/pubmed/33953677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.641848
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