Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway

Tanshinone IIA, a fat-soluble diterpenoid isolated from Salvia miltiorrhiza Bunge, has been shown to attenuate the cerebral ischemic injury. The aim of this study was to examine the effects on neuroprotection and microglia activation of Tanshinone IIA. Male Sprague-Dawley rats were subjected to midd...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Song, Zhibing, Feng, Jingjing, Zhang, Qian, Deng, Shanshan, Yu, Dahai, Zhang, Yuefan, Li, Tiejun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090935/
https://ncbi.nlm.nih.gov/pubmed/33953677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.641848
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