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PFOA Exposure Prior to Hepatocyte Differentiation Leads to Gene Expression Changes Implicated in Non-Alcoholic Fatty Liver Disease

Background: Perfluorooctanoic acid (PFOA), is a persistent fluorinated compound with oil and water repelling properties found in cookware, food packaging and municipal water systems. Adult animals exposed to PFOA develop hepatomegaly, fatty liver, peroxisome proliferation, and immunotoxicity. Rodent...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Hanke, Stephanie, Joshi, Apoorva, Fu, Weixuan, Wang, Paul, Tarapore, Pheruza, Simmons, Rebecca Anne, Pinney, Sara Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090679/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1003
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