Expression of IGF-1, IGF-1 Receptor and Growth Hormone Receptor in Hepatic Tissue in Adults Across the Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Background: Obesity is a state of relative growth hormone (GH) and insulin-like growth factor-1 (IGF-1) deficiency, and the GH/IGF-1 axis has been implicated in the pathophysiology of nonalcoholic fatty liver disease (NAFLD) and the progression to steatohepatitis (NASH) in preclinical models and hum...

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Pubblicato in:J Endocr Soc
Autori principali: Dichtel, Laura E, Subudhi, Sonu, Drescher, Hannah, Bartsch, Lea, Osganian, Stephanie, Chicote, Mark, Masia, Ricard, Bredella, Miriam, Bhatia, Sangeeta, Lauer, Georg, Miller, Karen Klahr, Corey, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Neuroendocrinology and Pituitary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090657/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1097
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