Mutation of the GnRHR Proximal Promoter AP-1 Element in Mice Results in Suboptimal GnRH Induction of LH and an Abnormal Reproductive Phenotype

Reproduction is regulated by the gonadotropins, LH and FSH, which are synthesized and secreted by pituitary gonadotrophs in response to hypothalamic GnRH in a pulse frequency dependent manner. The gonadotroph decodes GnRH pulsatility via the GnRH receptor (GnRHR), which increases in expression and c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Endocr Soc
Egile Nagusiak: Hausken, Krist N, Noel, Sekoni D, Kim, Han Kyeol, Carroll, Rona Stephanie, Kaiser, Ursula B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2021
Gaiak:
Neuroendocrinology and Pituitary
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1111
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