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DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption

BACKGROUND: Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland. METHODS: DEHP (vehicle, 50 mg/kg, and 500 mg/kg) was admini...

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Podrobná bibliografie
Vydáno v:Endocrinol Metab (Seoul)
Hlavní autoři: Kim, Min Joo, Kim, Hwan Hee, Song, Young Shin, Kim, Ok-Hee, Choi, Kyungho, Kim, Sujin, Oh, Byung-Chul, Park, Young Joo
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Endocrine Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090463/
https://ncbi.nlm.nih.gov/pubmed/33789034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2020.920
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