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DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption
BACKGROUND: Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland. METHODS: DEHP (vehicle, 50 mg/kg, and 500 mg/kg) was admini...
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| Publicado no: | Endocrinol Metab (Seoul) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Endocrine Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8090463/ https://ncbi.nlm.nih.gov/pubmed/33789034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2020.920 |
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