The Impact of ACTH on Peripheral Steroids Differs between Unilateral and Bilateral Primary Aldosteronism

Background: ACTH is thought to contribute to aldosterone excess in primary aldosteronism (PA), possibly via aberrant melanocortin type 2 receptor (MC2R) expression in aldosterone producing adenomas (APAs). Dynamic manipulation of the hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a n...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Tezuka, Yuta, Ishii, Kae, Zhao, Lili, Yamazaki, Yuto, Morimoto, Ryo, Sasano, Hironobu, Udager, Aaron, Satoh, Fumitoshi, Turcu, Adina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Cardiovascular Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089782/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.645
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