Visualization of Ca Channel Blocker on Human Adrenal Tissue by Mass Spectrometry Imaging ~Its Predominant Distribution at Aldosterone-Producing Cells ~

Primary aldosteronism (PA) is the main cause of secondary hypertension, accounting for approximately 5–10% of all hypertension. Amlodipine, a third-generation calcium channel blocker, is one of the most frequently administered pharmaceuticals medications of hypertension, binds specifically to Cav1.2...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Motomura, Naoki, Yamazaki, Yuto, Xin, Gao, Tezuka, Yuta, Omata, Kei, Ono, Yoshikiyo, Morimoto, Ryo, Satoh, Fumitoshi, Nakamura, Yasuhiro, Sasano, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Cardiovascular Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090254/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.619
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