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Efficient Restoration of Beta Cell Dedifferentiation by Calorie Restriction With High Fat/Low Carbohydrate Diet in Obese Diabetes Model and the Possible Role of GLP-1

In type 2 diabetes, pancreatic beta cells are gradually ‘exhausted’ and fall into beta cell dysfunction, which proceeds more severe insulin dependence. Among the proposed mechanisms of beta cell dysfunction such as endoplasmic reticulum stress and oxidative stress, the beta cell heterogeneity has at...

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Bibliografski detalji
Izdano u:J Endocr Soc
Glavni autori: Ishida, Emi, Lei, Xiao, Horiguchi, Kazuhiko, Matsumoto, Shunichi, Yoshino, Satoshi, Nakajima, Yasuyo, Yamada, Eijiro, Yamada, Masanobu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089540/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.896
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