Efficient Restoration of Beta Cell Dedifferentiation by Calorie Restriction With High Fat/Low Carbohydrate Diet in Obese Diabetes Model and the Possible Role of GLP-1

In type 2 diabetes, pancreatic beta cells are gradually ‘exhausted’ and fall into beta cell dysfunction, which proceeds more severe insulin dependence. Among the proposed mechanisms of beta cell dysfunction such as endoplasmic reticulum stress and oxidative stress, the beta cell heterogeneity has at...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Endocr Soc
Päätekijät: Ishida, Emi, Lei, Xiao, Horiguchi, Kazuhiko, Matsumoto, Shunichi, Yoshino, Satoshi, Nakajima, Yasuyo, Yamada, Eijiro, Yamada, Masanobu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2021
Aiheet:
Diabetes Mellitus and Glucose Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089540/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.896
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