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iPSC-Derived Human Hepatocytes as a Novel Model to Investigate Thyroid Hormone Action and Signaling

Thyroid hormone (TH) actions are essential to normal metabolism and neurologic function. Abnormal TH levels can lead to significant morbidity including metabolic abnormalities, cardiac disease, and obesity. TH action is mediated by the thyroid hormone receptor (TR) isoforms and their coregulators. I...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: De Oliveira, Lorraine Soares, Lee, Nora, Kaserman, Joseph, Vella, Kristen R, Wilson, Andrew, Hollenberg, Anthony Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089531/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1994
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