iPSC-Derived Human Hepatocytes as a Novel Model to Investigate Thyroid Hormone Action and Signaling

Thyroid hormone (TH) actions are essential to normal metabolism and neurologic function. Abnormal TH levels can lead to significant morbidity including metabolic abnormalities, cardiac disease, and obesity. TH action is mediated by the thyroid hormone receptor (TR) isoforms and their coregulators. I...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: De Oliveira, Lorraine Soares, Lee, Nora, Kaserman, Joseph, Vella, Kristen R, Wilson, Andrew, Hollenberg, Anthony Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Thyroid
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089531/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1994
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