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Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP(®)) Biosimilar, to Those of NESP(®) After a Single Subcutaneous or Intravenous Administration to Healthy Subjects

INTRODUCTION: Darbepoetin alfa (NESP(®) and ARANESP(®)) has a sustained erythropoietic activity with a longer half-life than conventional recombinant human erythropoietin. CKD-11101 is under clinical development as a biosimilar of darbepoetin alfa. The purpose of this study was to compare the pharma...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Jeon, Inseung, Oh, Jaeseong, Kwon, Yu-Kyung, Yoon, Seo Hyun, Cho, Joo-Youn, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089108/
https://ncbi.nlm.nih.gov/pubmed/33953543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S303772
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