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Oxidation shuts down an auto-inhibitory mechanism of von Willebrand factor
The blood protein von Willebrand factor (VWF) is a key link between inflammation and pathological thrombus formation. In particular, oxidation of methionine residues in specific domains of VWF due to the release of oxidants in inflammatory conditions has been linked to an increased platelet-binding...
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| Publicado no: | Proteins |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8089038/ https://ncbi.nlm.nih.gov/pubmed/33550613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.26055 |
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