Periodontitis‐compromised dental pulp stem cells secrete extracellular vesicles carrying miRNA‐378a promote local angiogenesis by targeting Sufu to activate the Hedgehog/Gli1 signalling

OBJECTIVES: Previously, our investigations demonstrated robust pro‐angiogenic potentials of extracellular vesicles secreted by periodontitis‐compromised dental pulp stem cells (P‐EVs) when compared to those from healthy DPSCs (H‐EVs), but the underlying mechanism remains unknown. MATERIALS AND METHO...

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Veröffentlicht in:Cell Prolif
Hauptverfasser: Zhou, Huan, Li, Xuan, Wu, Rui‐Xin, He, Xiao‐Tao, An, Ying, Xu, Xin‐Yue, Sun, Hai‐Hua, Wu, Li‐An, Chen, Fa‐Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088471/
https://ncbi.nlm.nih.gov/pubmed/33759282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13026
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