Intermedin(1-53) attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to be a key mechanism of macrophage apoptosis. In...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Zhang, Ya-Rong, Liu, Shi-Meng, Yu, Yan-Rong, Jia, Mo-Zhi, Tang, Chao-Shu, Qi, Yong-Fen, Lu, Wei-Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088440/
https://ncbi.nlm.nih.gov/pubmed/33934111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03712-w
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