Intermedin(1-53) attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to be a key mechanism of macrophage apoptosis. In...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Zhang, Ya-Rong, Liu, Shi-Meng, Yu, Yan-Rong, Jia, Mo-Zhi, Tang, Chao-Shu, Qi, Yong-Fen, Lu, Wei-Wei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088440/
https://ncbi.nlm.nih.gov/pubmed/33934111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03712-w
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