Intermedin(1-53) attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to be a key mechanism of macrophage apoptosis. In...

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Publicado no:Cell Death Dis
Main Authors: Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Zhang, Ya-Rong, Liu, Shi-Meng, Yu, Yan-Rong, Jia, Mo-Zhi, Tang, Chao-Shu, Qi, Yong-Fen, Lu, Wei-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088440/
https://ncbi.nlm.nih.gov/pubmed/33934111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03712-w
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