Intermedin(1-53) attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to be a key mechanism of macrophage apoptosis. In...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Zhang, Ya-Rong, Liu, Shi-Meng, Yu, Yan-Rong, Jia, Mo-Zhi, Tang, Chao-Shu, Qi, Yong-Fen, Lu, Wei-Wei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088440/
https://ncbi.nlm.nih.gov/pubmed/33934111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03712-w
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