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Exosome-Mediated Transfer of circ_0000338 Enhances 5-Fluorouracil Resistance in Colorectal Cancer through Regulating MicroRNA 217 (miR-217) and miR-485-3p

Exosomes are microvesicles secreted by body cells for intercellular communication. The circular RNA circ_0000338 was found to be present in extracellular vesicles and improve the chemoresistance of colorectal cancer (CRC) cells. However, the role of exosomal circ_0000338 in 5-fluorouracil (5-FU) res...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Zhao, Kui, Cheng, Xiaohui, Ye, Zhenyu, Li, Yecheng, Peng, Wei, Wu, Yongyou, Xing, Chungen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088270/
https://ncbi.nlm.nih.gov/pubmed/33722958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00517-20
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