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GW182 Proteins Restrict Extracellular Vesicle-Mediated Export of MicroRNAs in Mammalian Cancer Cells

MicroRNAs (miRNAs) are small regulatory RNAs of relatively long half-life in non-proliferative human cells. However, in cancer cells the half-lives of miRNAs are comparatively short. To understand the mechanism of rapid miRNA turnover in cancer cells, we explored the effect of target mRNAs on the ab...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Ghosh, Souvik, Mukherjee, Kamalika, Chakrabarty, Yogaditya, Chatterjee, Susanta, Ghoshal, Bartika, Bhattacharyya, Suvendra N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088265/
https://ncbi.nlm.nih.gov/pubmed/33685914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00483-20
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