Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

BACKGROUND: Autism spectrum disorder (ASD) is characterized by the core symptoms of impaired social interactions. Increasing evidence suggests that ASD has a strong genetic link with mutations in chromodomain helicase DNA binding protein 8 (CHD8), a gene encoding a chromatin remodeler. It has previo...

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Bibliographic Details
Published in:BMC Neurosci
Main Authors: Cherepanov, Stanislav M., Gerasimenko, Maria, Yuhi, Teruko, Furuhara, Kazumi, Tsuji, Chiharu, Yokoyama, Shigeru, Nakayama, Keiichi I., Nishiyama, Masaaki, Higashida, Haruhiro
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088024/
https://ncbi.nlm.nih.gov/pubmed/33933000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-021-00631-6
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