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Effects of self-assembled cell-penetrating peptides and their nano-complexes on ABCB1 expression and activity

OBJECTIVE(S): Doxorubicin (Dox) is one of the most well-known chemotherapeutics that are commonly applied for a wide range of cancer treatments. However, in most cases, efflux pumps like P-glycoprotein (P-gp), expel the taken drugs out of the cell and decrease the Dox bioavailability. Expression of...

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Detalles Bibliográficos
Publicado en:Iran J Basic Med Sci
Main Authors: Niazi, Mehri, Zakeri-Milani, Parvin, Soleymani-Goloujeh, Mehdi, Mohammadi, Ali, Sarfraz, Muhammad, Löbenberg, Raimar, Najafi-Hajivar, Saeedeh, Shahbazi-Mojarrad, Javid, Farshbaf, Masoud, Valizadeh, Hadi
Formato: Artigo
Idioma:Inglês
Publicado: Mashhad University of Medical Sciences 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087847/
https://ncbi.nlm.nih.gov/pubmed/33995950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2021.51675.11727
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