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Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study
OBJECTIVE(S): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered an important target candidate for antibody-based therapy. This study aimed to...
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| Wydane w: | Iran J Basic Med Sci |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Mashhad University of Medical Sciences
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087844/ https://ncbi.nlm.nih.gov/pubmed/33995947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2021.51709.11728 |
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