Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study

OBJECTIVE(S): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered an important target candidate for antibody-based therapy. This study aimed to...

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Bibliographic Details
Published in:Iran J Basic Med Sci
Main Authors: Navabi, Parnian, Ganjalikhany, Mohamad Reza, Jafari, Sepideh, Dehbashi, Moein, Ganjalikhani-Hakemi, Mazdak
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2021
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087844/
https://ncbi.nlm.nih.gov/pubmed/33995947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2021.51709.11728
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