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POU2F2 regulates glycolytic reprogramming and glioblastoma progression via PDPK1-dependent activation of PI3K/AKT/mTOR pathway

The POU Class Homeobox 2 (POU2F2) is a member of POU transcription factors family, which involves in cell immune response by regulating B cell proliferation and differentiation genes. Recent studies have shown that POU2F2 acts as tumor-promoting roles in some cancers, but the underlying mechanism re...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Rui, Wang, Mei, Zhang, Guanghui, Li, Yanping, Wang, Lulin, Cui, Hongjuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087798/
https://ncbi.nlm.nih.gov/pubmed/33931589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03719-3
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