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Interbase-FRET binding assay for pre-microRNAs

The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of small-molecule inhibitors of miR biogenesis. These inhibitors have the potential to (i) dissect miR mechanisms of action, (ii) discover new drug tar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bood, Mattias, del Nogal, Anna Wypijewska, Nilsson, Jesper R., Edfeldt, Fredrik, Dahlén, Anders, Lemurell, Malin, Wilhelmsson, L. Marcus, Grøtli, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087795/
https://ncbi.nlm.nih.gov/pubmed/33931703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88922-0
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