Whole-genome sequencing reveals rare off-target mutations in CRISPR/Cas9-edited grapevine

The CRISPR (clustered regularly interspaced short palindromic repeats)-associated protein 9 (Cas9) system is a powerful tool for targeted genome editing, with applications that include plant biotechnology and functional genomics research. However, the specificity of Cas9 targeting is poorly investig...

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Detalhes bibliográficos
Publicado no:Hortic Res
Main Authors: Wang, Xianhang, Tu, Mingxing, Wang, Ya, Yin, Wuchen, Zhang, Yu, Wu, Hongsong, Gu, Yincong, Li, Zhi, Xi, Zhumei, Wang, Xiping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087786/
https://ncbi.nlm.nih.gov/pubmed/33931634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41438-021-00549-4
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