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A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia

As more clinically-relevant genomic features of myeloid malignancies are revealed, it has become clear that targeted clinical genetic testing is inadequate for risk stratification. Here, we develop and validate a clinical transcriptome-based assay for stratification of acute myeloid leukemia (AML)....

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Bibliographic Details
Published in:Nat Commun
Main Authors: Docking, T. Roderick, Parker, Jeremy D. K., Jädersten, Martin, Duns, Gerben, Chang, Linda, Jiang, Jihong, Pilsworth, Jessica A., Swanson, Lucas A., Chan, Simon K., Chiu, Readman, Nip, Ka Ming, Mar, Samantha, Mo, Angela, Wang, Xuan, Martinez-Høyer, Sergio, Stubbins, Ryan J., Mungall, Karen L., Mungall, Andrew J., Moore, Richard A., Jones, Steven J. M., Birol, İnanç, Marra, Marco A., Hogge, Donna, Karsan, Aly
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087683/
https://ncbi.nlm.nih.gov/pubmed/33931648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22625-y
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