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Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance

Recent findings indicate that mitochondrial respiration regulates blood endothelial cell proliferation; however, its role in differentiating lymphatic endothelial cells (LECs) is unknown. We hypothesized that mitochondria could work as a sensor of LECs’ metabolic specific needs by determining their...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Ma, Wanshu, Gil, Hyea Jin, Liu, Xiaolei, Diebold, Lauren P., Morgan, Marc A., Oxendine-Burns, Michael J., Gao, Peng, Chandel, Navdeep S., Oliver, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087398/
https://ncbi.nlm.nih.gov/pubmed/33931446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe7359
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