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Targeting the myostatin signaling pathway to treat muscle loss and metabolic dysfunction

Since the discovery of myostatin (MSTN; also known as GDF-8) as a critical regulator of skeletal muscle mass in 1997, there has been an extensive effort directed at understanding the cellular and physiological mechanisms underlying MSTN activity, with the long-term goal of developing strategies and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Autor principal: Lee, Se-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087205/
https://ncbi.nlm.nih.gov/pubmed/33938454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI148372
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