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Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight

The melanocortin 4 receptor (MC4R) plays a critical role in the long-term regulation of energy homeostasis, and mutations in the MC4R are the most common cause of monogenic obesity. However, the precise molecular and cellular mechanisms underlying the maintenance of energy balance within MC4R-expres...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Wang, Yi, Bernard, Adelaide, Comblain, Fanny, Yue, Xinyu, Paillart, Christophe, Zhang, Sumei, Reiter, Jeremy F., Vaisse, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087202/
https://ncbi.nlm.nih.gov/pubmed/33938449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI142064
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