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Detection of autoreactive CD4(+) T cells by MHC class II multimers in HLA-linked human autoimmune diseases
Recognition of self-peptides in association with distinct HLA class II alleles by autoreactive CD4(+) T cells is central for loss of immunological tolerance leading to autoimmune disease. However, identifying immunodominant self-peptides and characterizing autoreactive T cells is challenging. In thi...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087195/ https://ncbi.nlm.nih.gov/pubmed/33938450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI148674 |
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