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Cathepsin S regulates class II MHC processing in human CD4(+) HLA-DR(+) T cells

While it has long been known that human CD4(+) T cells can express functional class II MHC molecules, the role of lysosomal proteases in T cell class II MHC processing and presentation pathway is unknown. Using CD4(+) T cell clones that constitutively express class II MHC, we determined that catheps...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Costantino, Cristina Maria, Ploegh, Hidde L., Hafler, David A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752291/
https://ncbi.nlm.nih.gov/pubmed/19553543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900921
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