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Cathepsin S regulates class II MHC processing in human CD4(+) HLA-DR(+) T cells
While it has long been known that human CD4(+) T cells can express functional class II MHC molecules, the role of lysosomal proteases in T cell class II MHC processing and presentation pathway is unknown. Using CD4(+) T cell clones that constitutively express class II MHC, we determined that catheps...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752291/ https://ncbi.nlm.nih.gov/pubmed/19553543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900921 |
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