Overexpression of hepatic serum amyloid A1 in mice increases IL-17-producing innate immune cells and decreases bone density

Serum amyloid A (SAA) is an acute-phase protein produced primarily in the liver that plays a key role in both the initiation and maintenance of inflammation. Rapidly secreted SAA induces neutrophilia at inflammatory sites, initiating inflammation and inducing the secretion of various cytokines, incl...

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Pubblicato in:J Biol Chem
Autori principali: Choi, Minjee, Park, Song, Yi, Jun Koo, Kwon, Wookbong, Jang, Soyoung, Kim, Si-Yong, Yu, Wookyung, Kim, Myoung Ok, Ryoo, Zae Young, Choi, Seong-Kyoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086136/
https://ncbi.nlm.nih.gov/pubmed/33781747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100595
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