Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis

Neuroinflammation by activated microglia and astrocytes plays a critical role in progression of amyotrophic lateral sclerosis (ALS). Interleukin-19 (IL-19) is a negative-feedback regulator that limits pro-inflammatory responses of microglia in an autocrine and paracrine manner, but it remains unclea...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Komiya, Hiroyasu, Takeuchi, Hideyuki, Ogawa, Yuki, Suzuki, Kosuke, Ogasawara, Akihiro, Takahashi, Keita, Azuma, Yasu-Taka, Doi, Hiroshi, Tanaka, Fumiaki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086093/
https://ncbi.nlm.nih.gov/pubmed/33931083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00785-8
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