Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first‐line platinum chemotherapy in high grade serous ovarian cancer

BACKGROUND: In high grade serous ovarian cancer (HGSOC), there is a spectrum of sensitivity to first line platinum‐based chemotherapy. This study molecularly characterizes HGSOC patients from two distinct groups of chemotherapy responders (good vs. poor). METHODS: Following primary debulking surgery...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Weberpals, Johanne I., Pugh, Trevor J., Marco‐Casanova, Paola, Goss, Glenwood D., Andrews Wright, Natalie, Rath, Prisni, Torchia, Jonathon, Fortuna, Alexander, Jones, Gemma N., Roudier, Martine P., Bernard, Laurence, Lo, Bryan, Torti, Dax, Leon, Alberto, Marsh, Kayla, Hodgson, Darren, Duciaume, Marc, Howat, William J., Lukashchuk, Natalia, Lazic, Stanley E., Whelan, Doreen, Sekhon, Harmanjatinder S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085970/
https://ncbi.nlm.nih.gov/pubmed/33811746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3831
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