Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first‐line platinum chemotherapy in high grade serous ovarian cancer

BACKGROUND: In high grade serous ovarian cancer (HGSOC), there is a spectrum of sensitivity to first line platinum‐based chemotherapy. This study molecularly characterizes HGSOC patients from two distinct groups of chemotherapy responders (good vs. poor). METHODS: Following primary debulking surgery...

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Bibliografiset tiedot
Julkaisussa:Cancer Med
Päätekijät: Weberpals, Johanne I., Pugh, Trevor J., Marco‐Casanova, Paola, Goss, Glenwood D., Andrews Wright, Natalie, Rath, Prisni, Torchia, Jonathon, Fortuna, Alexander, Jones, Gemma N., Roudier, Martine P., Bernard, Laurence, Lo, Bryan, Torti, Dax, Leon, Alberto, Marsh, Kayla, Hodgson, Darren, Duciaume, Marc, Howat, William J., Lukashchuk, Natalia, Lazic, Stanley E., Whelan, Doreen, Sekhon, Harmanjatinder S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Clinical Cancer Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085970/
https://ncbi.nlm.nih.gov/pubmed/33811746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3831
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