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Trials to Overcome Drug Resistance to EGFR and ALK Targeted Therapies – Past, Present, and Future

Molecularly targeted agents are changing the therapeutic landscape in advanced non-small cell lung cancer. Since the discovery of sensitizing mutations in the epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) domain, clinical investigations have focused on optimizing the e...

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Detalhes bibliográficos
Main Authors: Spaans, Johanna N., Goss, Glenwood D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145253/
https://ncbi.nlm.nih.gov/pubmed/25221748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00233
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