MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders. Here, we measured miR-223 expression in acute and intercritical gout patients, after which we used RAW264.7 macrophages transfected wit...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Quan-Bo, Zhu, Dan, Dai, Fei, Huang, Yu-Qin, Zheng, Jian-Xiong, Tang, Yi-Ping, Dong, Zeng-Rong, Liao, Xia, Qing, Yu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085756/
https://ncbi.nlm.nih.gov/pubmed/33935726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.637415
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