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Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH
BACKGROUND: Mitochondrial uncouplers shuttle protons across the inner mitochondrial membrane via a pathway that is independent of adenosine triphosphate (ATP) synthase, thereby uncoupling nutrient oxidation from ATP production and dissipating the proton gradient as heat. While initial toxicity conce...
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| Publicado no: | Mol Metab |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085597/ https://ncbi.nlm.nih.gov/pubmed/33545391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101178 |
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