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Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous stu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Junren, Chen, Xiaofang, Xie, Huiqiong, Zhang, Gangmin, Li, Yanpeng, Yin, Xiaoyu, Cao, Yuqing, Gao, Yanan, Li, Yue, Zhang, Fu, Peng, Cheng, Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
https://ncbi.nlm.nih.gov/pubmed/33935784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660757
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