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Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous stu...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Junren, Chen, Xiaofang, Xie, Huiqiong, Zhang, Gangmin, Li, Yanpeng, Yin, Xiaoyu, Cao, Yuqing, Gao, Yanan, Li, Yue, Zhang, Fu, Peng, Cheng, Peng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
https://ncbi.nlm.nih.gov/pubmed/33935784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660757
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