Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous stu...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Junren, Chen, Xiaofang, Xie, Huiqiong, Zhang, Gangmin, Li, Yanpeng, Yin, Xiaoyu, Cao, Yuqing, Gao, Yanan, Li, Yue, Zhang, Fu, Peng, Cheng, Peng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
https://ncbi.nlm.nih.gov/pubmed/33935784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660757
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