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Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous stu...

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Publicado en:Front Pharmacol
Main Authors: Junren, Chen, Xiaofang, Xie, Huiqiong, Zhang, Gangmin, Li, Yanpeng, Yin, Xiaoyu, Cao, Yuqing, Gao, Yanan, Li, Yue, Zhang, Fu, Peng, Cheng, Peng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
https://ncbi.nlm.nih.gov/pubmed/33935784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660757
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