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Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous stu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Junren, Chen, Xiaofang, Xie, Huiqiong, Zhang, Gangmin, Li, Yanpeng, Yin, Xiaoyu, Cao, Yuqing, Gao, Yanan, Li, Yue, Zhang, Fu, Peng, Cheng, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085555/
https://ncbi.nlm.nih.gov/pubmed/33935784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.660757
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