Detecting Gene-Environment Interaction for Maternal Exposures Using Case-Parent Trios Ascertained Through a Case With Non-Syndromic Orofacial Cleft

Two large studies of case–parent trios ascertained through a proband with a non-syndromic orofacial cleft (OFC, which includes cleft lip and palate, cleft lip alone, or cleft palate alone) were used to test for possible gene–environment (G × E) interaction between genome-wide markers (both observed...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Zhang, Wanying, Venkataraghavan, Sowmya, Hetmanski, Jacqueline B., Leslie, Elizabeth J., Marazita, Mary L., Feingold, Eleanor, Weinberg, Seth M., Ruczinski, Ingo, Taub, Margaret A., Scott, Alan F., Ray, Debashree, Beaty, Terri H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085423/
https://ncbi.nlm.nih.gov/pubmed/33937227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.621018
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