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An affinity-based, cysteine-specific ATP analog for kinase-catalyzed crosslinking
Kinases mediate cell signaling pathways by catalyzing protein phosphorylation. Irregularities in kinase activity are directly associated with disease conditions. Therefore, methods to identify substrates of a particular kinase are needed to understand signaling cascades in normal and diseased states...
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| Publié dans: | Angew Chem Int Ed Engl |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8084585/ https://ncbi.nlm.nih.gov/pubmed/33619842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202014047 |
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