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Tyrosine sulfation and O-glycosylation of chemoattractant receptor GPR15 differentially regulate interaction with GPR15L

GPR15 is a G-protein-coupled receptor (GPCR) that directs lymphocyte homing to the colon and skin. Recent studies have identified a chemokine-like protein GPR15L (also known as C10orf99) as a functional ligand of GPR15. In this study, we examined the structural elements that regulate the GPR15–GPR15...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Okamoto, Yukari, Shikano, Sojin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084577/
https://ncbi.nlm.nih.gov/pubmed/33758080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.247833
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